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Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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How Does Sildenafil Work?

Sildenafil works by relaxing the blood vessels in the penis, allowing for increased blood flow and the ability to achieve an erection when sexually stimulated.

Sildenafil works by inhibiting the enzyme PDE5, which is responsible for breaking down cyclic guanosine monophosphate (cGMP). cGMP is essential for relaxing the blood vessels, allowing blood to flow into the penis, creating an erection.

Sildenafil works byutralising the effects of phosphodiesterase type 5 (PDE5) inhibitors, which block the action of PDE5.

Viagra has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Viagra use include:

  • Headache
  • Heartburn
  • Congestion
  • Nasal bleeding (bloody nose)
  • Nausea
  • Diarrhea
  • Muscle aches or pains
  • Flushing
  • Facial pain or tenderness
  • Vision changes
  • Light sensitivity

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Viagra. Viagra can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any nitrate medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Show Moreuspressant FDA Warnings

Viagra can increase the risk of low blood pressure, making it more likely that you will experience these side effects. Viagra can also affect the way certain medications work, such as nitrates, inducers, or Viagra-type drugs, in addition to those commonly used to treat heart problems. Viagra can interact with alcohol, so you should avoid any legal or controlled substances while taking Viagra.

Common Side Effects of Viagra

Side effects from Viagra include:

  • Indigestion
  • Pale depression
  • Drowsiness

If you experience any of the above side effects, seek medical attention immediately.

As with all prescription medications, inform your doctor if you have any medical conditions, especially the following:

  • A heart problem
  • Liver problems
  • Stomach problems or bleeding
  • Stomach bleeding or problems with your blood flow
  • Stomach problems or problems with your blood flow problems in your stomach or intestines

As with the above, inform your doctor about any and all medications, prescription drugs, and supplements you are taking. Viagra can affect the way other medications work, such as nitrates, in addition to those commonly used to treat heart problems. Viagra can affect the way other medications in Viagra work, such as those used to treat male impotence.

If you have any changes to your health status or health condition, contact your doctor sooner before taking Viagra.

Tell your doctor if you have any changes in the way your heart works, like recent heart attack or stroke, or how you look in your 30s or low.

In addition, let your doctor know if you have recently had a heart attack, conditions that affect the heart, or how you react to medications like Viagra.

Possible Side Effects

These are symptoms of a severe adverse reaction to this medication that requires immediate treatment.

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